can glp 1 reverse insulin resistance GLP1-GIP receptor co-agonists: a promising evolution in the treatment of type 2 diabetes | Acta Diabetologica GLP-1 Agonist Effects on Glucagon

63 In a large-scale real-world study, the use of GLP-1 receptor agonists in patients with T2DM was also shown to increase the risk of intestinal obstruction compared to sodiumglucose cotransporter-2 (SGLT-2) inhibitors

But we know that when you take them for years, if you have heart disease, that youre more likely to be alive than if you get a placebo instead

Yoo JW, Shin YJ, Ma X, Son YH, Jang HM, Lee CK, Kim DH (2022) The alleviation of gut microbiota-induced depression and colitis in mice by anti-inflammatory probiotics NK151, NK173, and NK175

Reduce the amount of sugar released by your liver

Alternatively, agents from different classessuch as SGLT-2 inhibitors or DPP-4 inhibitorscould be discussed if glycaemic targets allow