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Similarly, 5-methoxytryptophan (5-MTP) inhibits fibroblast-to-myofibroblast transition and ECM protein expression by downregulating TGF-/Smad3 and PI3K/AKT pathways, thereby limiting fibroblast proliferation and migration [113]

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Up to 50% improvement in cognitive performance and mood-related symptoms has been reported in patients treated with B12 injections, especially in those with mild deficiency

In the traumatic brain injury model, SDC-1 in rat cerebral tissue decreased while increased in serum