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Lipid-induced signaling causes release of inflammatory extracellular vesicles from hepatocytes
Juster-Switlyk K, Smith AG
As such, it is involved in many biological processes, including the breakdown of fats, the reduction of serum cholesterol, serotonin activity modulation, gene expression, and insulin signal transduction
It was FDA-approved in 2010 as a weight loss medication for Netherlands HIV patients suffering from lipodystrophy, a condition that leads to an accumulation of fat (adipose tissue) in the abdominal area
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