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Sun S, Yang Y, Xiong R, Ni Y, Ma X, Hou M, et al
Small (2022) 18(16):21063422
67 , 355367 (2011) Nicholls, R
While FDA does not limit compounding to drug shortages and we believe there are paths to continue offering access to certain compounded GLP-1s after the shortage ends, we cannot guarantee that we will be able to continue offering these products in the same manner, to the same extent, or at all, due to a variety of factors outside our control, including supply chain, intellectual property, regulatory and resource allocation matters.) On October 2, 2024, this risk materialized when FDA announced on its website that Lilly had resolved the tirzepatide shortage, meaning that companies making and distributing compounded copies needed to stop in their tracks, regardless of ongoing patient care
Two potential sources of TL heritability include inherited variation in non-telomeric regions (e.g., single nucleotide polymorphisms affecting telomere maintenance) and TL variability in gametes which produce zygotes (the direct inheritance)
