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In comparison, the prevalence of obesity in adults increased from approximately 28% in 19992000 to 43% in 20172018 [6]
To combat this, Dr
Mutat Res (2010) 704:1529
IGF-1 LR3 bypasses the pituitary and GH entirely, directly activating IGF-1R at the tissue level
However, because it affects weight, insulin, and metabolism, it can lead to indirect hormonal changes
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