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Due to accumulation of metabolic intermediates, impaired carnitine biosynthesis, reduced protein intake, and increased removal of carnitine through hemodialysis (HD), patients who undergo routine HD usually present with plasma carnitine insufficiency [54]
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This study took place over a 12-week time period while all subjects were randomized and the experiment was double-blinded for semaglutide versus a placebo compound and an active control
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