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The next day, on February 6, 2026, FDA issued its enforcement announcement, marking the latest in FDAs ongoing efforts to regulate the compounding of GLP-1 medications
Compounded medications from licensed 503A pharmacies contain the same active pharmaceutical ingredients as brand names but cost 70-85% less because they avoid manufacturer overhead
A phase II trial focusing on individuals with overweight or obesity, coupled with hypertension or dyslipidemia but without T2D, found that cagrilintide (2.4 mg) alongside diet and exercise, led to a 10% body weight reduction compared to 3% with placebo over 26 weeks [99]
What symptoms should I watch for and report
Call the clinic between visits rather than waiting for your next appointment if nausea or vomiting is persistent enough to affect hydration, if constipation does not resolve with the measures above, if you are unable to keep food or fluids down, or if you develop severe or persistent abdominal pain
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