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Targeting the components of RAAS, such as angiotensin-converting enzyme inhibitors (ACE inhibitors) or angiotensin receptor blockers (ARBs), is a common therapeutic approach to mitigate renal tubular injury and retard DKD progression
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Ethosomes specifically possess elevated ethanol concentrations that augment stratum corneum lipid fluidity and vesicle pliability, thus enhancing the transdermal transit of poorly water-soluble pharmaceuticals [295]
ZDHHC5 knockdown inhibits NLRP3 oligomerization, NLRP3-NEK7 interactions, and the formation of intracellular ASC macroaggregates, reducing mices inflammatory response (74)
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