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It has been demonstrated that oxidative stress-mediated GSH depletion is crucial in controlling transient outward K+ currents in rat ventricular myocytes, which may be the cause of diabetes-related decreased contractility and aberrant electrical characteristics

further notes that a restricted maintenance dose of just four injections per year is what is normally allowed, which can leave people physically and mentally unable to contribute to either family or society, and lead to permanent neurological damage

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Biol Psychiatry 54 : 13301337

GHK-Cu contributes to redox balance and extracellular matrix homeostasis by stimulating metalloproteinase activity and increasing antiprotease expression, while also participating in the regulation of copper-dependent antioxidant enzymes