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Furthermore, these chosen strains exhibited notable vitality throughout fermentation and storage of fermented milk at 4 C

this warrants ongoing monitoring No unexpected serious cardiovascular signals were identified during the limited Phase 2 follow-up period, though the trials were neither designed nor powered to assess cardiovascular outcomes, and longer-term data are not yet available At present, the overall safety profile appears broadly consistent with other GLP-1-based therapies, but definitive conclusions cannot be drawn until Phase 3 data and post-marketing surveillance are available

Estrogen management sometimes becomes necessary, particularly for men with higher body fat percentages or those prone to aromatization

doi:10.1007/s10815-020-01987-0

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