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Therefore, the combined use of GLP-1 RAs with therapies targeting intrahepatic pathways, such as thyroid hormone receptor (THR-) agonists, fibroblast growth factor-21 (FGF21) analogues, and peroxisome proliferator-activated receptor (PPAR) agonists, presents a promising approach for MASH treatment
& Turek, F
A diferencia de las inyecciones de GLP-1, que cuentan con dcadas de investigacin clnica y ensayos controlados aleatorizados en miles de pacientes, los sistemas transdrmicos an no han demostrado eficacia clnica en humanos a gran escala
Life Sci 244:117232 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S et al (2021) Guidelines for the use and interpretation of assays for monitoring autophagy
4%), leading to therapy interruption in 16% of survodutide recipients vs
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