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Separating the effects of the drug from the effects of the drug-induced weight loss is methodologically challenging
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J Med Chem 66:36563663 Zhang X, Belousoff MJ, Liang Y-L, Danev R, Sexton PM et al (2021) Structure and dynamics of semaglutide and taspoglutide bound GLP-1R-Gs complexes
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However, in the complex molecular processes that characterize tumorigenesis, iron also plays a central role in ferroptosis, a form of non-apoptotic regulated cell death characterized by the lethal accumulation of lipid peroxidation products and ROS derived from iron metabolism (362, 363)
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