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10.1038/s41467-021-24734-0 44 LiZ.FengP.-P.ZhaoZ.-B.ZhuW.GongJ.-P.DuH.-M
Testing for vitamin B12 or folate deficiency is not routinely included in blood work ordered at an annual physical exam
PRLMs may exert multifaceted neuroprotective effects in VaMCI by suppressing oxidative stress, reducing neuronal apoptosis, enhancing synaptic plasticity, promoting resolution of inflammation, and maintaining metabolic homeostasis in the brain
Studies on the use of non-denaturing agents such as N -lauryl sarcosine, dimethyl sulfoxide (DMSO), 5% n -propanol, mild non-ionic detergents, high pH buffers, and low denaturant concentration that preserve the native-like state of the fusion proteins have been reported [52,53,54,55,56,57]
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