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They are contraindicated in patients with renal impairment manifested by hypercreatininemia and reduction of glomerular filtration rate
We thank our funders, the Novo Nordisk ISS Scheme, the National Institute for Health Research (NIHR) UCL/UCLH Biomedical Research Centre and the Sir Jules Thorne Charitable Trust, for supporting our work
doi:10.1038/379069a0 20
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