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Reverse transcription to generate cDNA was performed using TaqMan Reverse Transcriptase Kit according to the manufacturers instructions (Cat

In contrast, treatment effects evaluated by the trial product estimand assumed that patients received the study drug for the duration of the trial and did not receive any additional blood glucose lowering medications (thereby aiming to reflect the effects of the study medications without the confounding effects of rescue medication or any other changes in glucose-lowering medication) [21]

Once again, Sage posted public criticism of Mike without using his name, stoking the fire of what was already sure to grow into another controversy

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