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Figure 2 Unlike erastin, RSL3another classical ferroptosis inducerdoes not act via GSH depletion
Therefore, maintaining a balanced diet rich in fiber and probiotics can be beneficial for patients on GLP-1 therapy, helping to mitigate some of the gastrointestinal side effects
In sensible cosmetic concentrations this is not a general concern, but it argues against casual escalation of dose or concentration in the belief that more is better
More importantly for the tachyphylaxis question, a single snapshot emptying measured once, early in treatment cannot reveal whether the effect is durable
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