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More specifically, Lilly argues that retatrutide is a protein pursuant to FDAs 21 CFR 600.3(h)(6) which defines protein as any alpha amino acid polymer with a specific, defined sequence that is greater than 40 amino acids in size. According to Lilly, retatrutide is a protein because it has a specific, defined sequence of 41 amino acids, i.e
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Additionally, in the trial examining alcohol use disorder, a significant reduction in alcohol consumption was observed only in a specific subgroup of patients with obesity, suggesting that patient characteristics, such as BMI, might influence treatment outcomes
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