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Vitamin C is generally well-tolerated, but L-carnitine often absorbs better when taken with a small amount of carbohydrates

Acetoacetate and beta-hydroxybutyrate are excreted through the kidneys into urine, while acetone is primarily eliminated through respiration (causing characteristic "fruity" breath)

Ideal candidates typically include adults with type 2 diabetes who have inadequate glycaemic control (HbA1c above individualised target) despite treatment with metformin and/or other oral agents, particularly those with additional cardiovascular or renal risk factors

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Large doses of levocarnitine may cause diarrhea