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Reprod BioMed Online (2019) 39:33242

Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses

In a clinical trial participants lost an average of 15% of their body weight after 68 weeks

As a cosmeceutical, peptides act on fibroblasts to stimulate collagen and neuromuscular junctions to relax facial muscles while also providing ample essential trace elements to promote tissue repair and prevent collagen breakdown, all potentially attenuating rhytids

Promising avenues include targeting tau pathology, neuroinflammation, mitochondrial dysfunction, brain insulin resistance, vascular integrity, and infectious triggers