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In addition, treatment effects estimated using MMRM analyses are typically larger than those seen with MI analyses since the MMRM estimates the treatment effect while participants are adhering to the investigational drug, whereas MI-based estimates (reflecting the intent-to-treat approach) are irrespective of adherence
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Whether and how any of this translates into a meaningful outcome for a specific individual is exactly the kind of question that belongs in a clinical evaluation, not a generalized article
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