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For deficiency without neurological involvement or for borderline levels, oral supplementation with high-dose cyanocobalamin (1000-2000 mcg daily) is often effective, as approximately 1% of an oral dose is absorbed through passive diffusion even in the absence of intrinsic factor
experts therefore recommend using such products only when the potential maternal benefit clearly outweighs theoretical risk and under obstetric supervision
It involves weekly injections for one month
[7] Population pharmacokinetic modeling reveals a biphasic disposition (distribution half-life 15-30 minutes
Research on glycine supplementation shows modest benefits for collagen synthesis and some metabolic parameters
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