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if a patient is on blood pressure-lowering drugs (such as beta blockers, alpha-1 blockers, or vasodilators), niacinamide injections could lead to an additive drop in blood pressure

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( National Institutes of Health, Office of Dietary Supplements

[44] [41] Vitamin B 12 is not one of the supplements recommended by the World Health Organization for healthy women who are pregnant, [14] however, vitamin B 12 is often suggested during pregnancy in a multivitamin along with folic acid [45] [46] especially for pregnant mothers who follow a vegetarian or vegan diet