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In another report, the PEGylation of these nanocarriers loaded with anthocyanins resulted in an enhanced efficacy in the prevention of neurodegenerative disorders such as AD, compared to the uncoated specimen both in vivo and in vitro (Kim et al., 2017)

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Subsequent studies evaluating the possible contribution of this polymorphism to the maternal risk of having a DS child were conflicting (Table 1), but two recent meta-analyses (Yang et al., 2013