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emphasized that SPRA is characterized by plasma blast expansion, follicular helper T cell (Tfh) infiltration, and the formation of synovial tertiary lymphoid structures (TLS), whereas such adaptive immune markers are notably absent in OA and SNRA ( In summary, although both osteoarthritis and rheumatoid arthritis are associated with the immune system, their immunological mechanisms and treatment approaches differ significantly

FIGURE 2 Investigating ferroptosis not only expands our knowledge of the intricate mechanisms underlying migraines, but it also creates new opportunities for locating possible targets for treatment

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560 In SLE patients, B cells exhibit increased mTORC1 activity, which is correlated with increased lactate production, indicating a metabolic shift toward glycolysis