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Although a single RCT failed to observe a statistically significant improvement in HOMA-IR (85), this discrepancy is more likely attributable to limited sample sizes, restricted follow-up windows, and heterogeneity in baseline metabolic phenotypes rather than a lack of efficacy
At AgeRejuvenation, CJC-1295 and Sermorelin are often paired with broader hormone and metabolic care so the team can address deeper drivers like insulin resistance, thyroid issues, or chronic fatigue, rather than masking symptoms
One consideration that partially offsets the bioavailability difference involves absorption kinetics
It is important to distinguish between an expiration date and a beyond-use date (BUD), as they serve different purposes in clinical safety
doi: 10.2337/db13-0140 21 MeierJJ
