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Introduction The development of new compounds in recent decades has substantially improved the pharmacotherapy of type 2 diabetes (T2D) by improving achievement of metabolic targets while mitigating specific side effects (e.g., weight gain, hypoglycemia) frequently observed in patients treated with traditional hypoglycemic drugs such as insulin and sulfonylureas
Conformational changes are generally small, involve the protein backbone, and are often accompanied by a local increase in protein disorder (Mallis et al., 2000
Many people are eating smaller portions, prioritizing protein, and looking for options that feel satisfying without being heavy or overly sweet
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