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[15] [1] Those experiencing gastrointestinal side effects from GLP-1 therapy (nausea, vomiting, diarrhoea) should exercise caution with allulose, as additive effects on gut symptoms are theoretically possible

Mechanistic and translational studies suggest that the underlying metabolic dysregulation in patients with obesity, particularly hyperglycemia and insulin resistance, contributes to altered immune cell function and low-grade systemic inflammation

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This matches a broader finding that CVS plans technically cover Wegovy in just 18% of their employer-sponsored formularies (2026 data) ( [4] )

Intravenous NAC is the standard of care, providing cysteine to regenerate glutathione (Smilkstein et al., N Engl J Med, 1988) [32]