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The authors further explored the relevant signaling pathways and found that mitogen-activated protein kinase (MAPK) and nuclear factor-B (NF-B) were repressed by liraglutide treatment (22)

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For the quantification of Kim-1 and Ngal stainings (staining score), 5 and 10 images (2 at each magnification, for a total of 4 per mouse) were likewise graded with 0 (no staining), 1 (mild), 2 (moderate), or 3 (intense) based on intensity and area of the staining