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Since calcium signaling is required for many pro-inflammatory cascades, this hyperpolarization effectively puts the brakes on inflammatory cytokine production

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Comparison with Mendelian randomization analyses of BMI and T2D genetic liability Genetic association data for BMI were obtained from a meta-analysis of GWAS conducted in 694,649 individuals 72 and for T2D from the DIAMANTE consortium (80,154 cases and 853,816 controls) 73