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It was suspected that there would also be hormonal regulation of metabolism, and after the discovery of insulin, researchers began to think about incretins, substances that could regulate insulin secretion similar to the regulation of exocrine function by excretins [2]
Adding glucagon activity is counter-intuitive, because glucagon raises blood sugar
They appear on dendritic cells, the scouts of the immune system
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doi: 10.1053/j.gastro.2013.04.006 61 ChangLSultanSLemboAVerneGNSmalleyWHeidelbaughJJ
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