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The trial enrolled 445 participants with obesity (BMI 27) who also had moderate-to-severe knee osteoarthritis
Sources: Science Daily, The Lancet Psychiatry
Tirzepatide is injected subcutaneously, usually in the abdomen, thigh, or upper arm
Weight regain less likely upon cessation of medication Low price makes consistency easier and leads to better results Inconsistent use may lead to regain but because of low price, compliance is far easier May switch to GLP-1 Program if wanted Best program for most people Our most popular program Uses Wegovy and related medications Rarely covered by insurance Requires self-injection May produce slightly more weight loss Requires filling prescription at retail pharmacy May require months-long gradual dose increase to avoid serious side effects Not a cure: rapid weight regain reported after stopping High price makes consistent use difficult and may cause treatment failure Inconsistent use leads to weight regain and extreme price makes this more likely and more common May switch to traditional program if desired Best for wealthy people Price limits popularity $86-$120 $750-$1450 *QUESTION: When do You Have to Choose Between the Two Programs
In the brain, GLP-1RAs perform anti-inflammatory, antioxidant, and anti-apoptotic functions (12)
