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15 Months of Progress After 15 months of consistent treatment with Tirzepatide at a dose of 7.5 mg/week, JHs results were nothing short of inspiring: Follow-Up Bioimpedance Spectroscopy Measurements: Weight: 162 lbs (a 78-lb loss) Body Fat Percentage: 32.9% (down 12.8%) BMI: 23.3 (a reduction of 10.1 kg/m) Body Fat Mass: 53.2 lbs (a decrease of 56 lbs) Lean Body Mass: 109 lbs (down 21 lbs) Skeletal Muscle Mass: 59 lbs (loss of only 12 lbsjust 15% of her total weight loss, less than the typical 20%) ECW/TBW: Slight improvement in the right leg to 0.396

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Additionally, the severely degenerated NP tissues had higher levels of pro-inflammatory cytokines, such as interleukin-1 (IL-1) and interleukin-6 (IL6), in comparison with the mildly degenerated ones, signifying a hyperinflammatory microenvironment in disks (Fig