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LPO is implicated in human cataractogenesis because the toxic peroxidation products induce fragmentation of soluble lens proteins and damage vital membrane structures, correlating with an increase in lens opacity and changes in the refractive properties of the lens 23
Beneficial properties are evident in that it is involved in the elimination of pathogenic viruses (including influenza and COVID19), bacteria, fungi, protozoan parasites and helminths, while during fungal infections, transcellular biosynthesis of LTB 4 orchestrates neutrophil swarming, a defence mechanism triggered by targets larger than the capacity of a single neutrophil to phagocytose
Pediatr Nephrol 28:507510
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