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This variation reflects differences in baseline metabolism, activity level, medication adherence, and genetic factors affecting peptide pathway sensitivity

Importantly, in this case, the details of the crucial nAb activities in vivo were complex and not fully captured by in vitro neutralization assays, which typically involve inhibition of HPV pseudovirus infection in an epithelial cell line by nAb 179

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After 45 min of Hoechst 33342 staining, medium was replaced with medium containing the different concentrations of AQ-QI, DEAQ-QI, AQ, and DEAQ and monitored for 24 h