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It upregulates genes that code for collagen I, III, and IV while simultaneously suppressing genes associated with collagen degradation
That should be the other way round, of course: injections are the Gold standard in treating symptomatic B12 deficiency, oral medication is not
Retinoic acid and arsenic trioxide for acute promyelocytic leukemia
The target genes for the antioxidant response encode a set of enzymes and other proteins that scavenge free radicals, neutralise electrophiles or up-regulate the critical cellular thiol, glutathione
Specifically, to simulate the in vitro expansion for ACI, human chondrocytes were expanded to a population doubling level (PDL) 9 to represent chondrocytes ready for implantation
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