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The prevailing model held that these drugs act directly on GLP-1 receptors in the brain, while our study provides evidence for an alternative pathway. For this study, the researchers used the weight-loss drug liraglutide, marketed under the brand names Victoza and Saxenda

It enrolled 17,605 participants, average age 61.6 years, who were obese or overweight (BMI average = 33 kg/m2) withou t diabetes but with prior heart attack, stroke or peripheral artery disease

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Long-term acetyl-L-carnitine treatment in Alzheimer's disease Neurology 1991