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Dose, rate of weight loss, baseline BMI, and individual reproductive hormone baseline all influence outcomes

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IV administration also introduces risks that oral supplementation does not: Contamination or excessive endotoxin exposure Sterility and compounding failures Infusion reactions Venous irritation or infection Dosing errors Additional cost and clinical complexity The FDA has reported adverse events among patients who received injectable compounded glutathione made with an unsuitable dietary ingredient

However, biweekly dosing represents off-label use not supported by FDA labeling or clinical trial evidence

Monitoring vital signs, fluid balance, and electrolyte levels helps identify dehydration, electrolyte imbalances, and prevents complications such as fluid overload or cardiac dysrhythmias