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KLOW taken simultaneously with insulin-sensitizing peptides (like metformin analogs) creates conflicting signals at the glucose metabolism level
Therefore, the combined use of GLP-1 RAs with therapies targeting intrahepatic pathways, such as thyroid hormone receptor (THR-) agonists, fibroblast growth factor-21 (FGF21) analogues, and peroxisome proliferator-activated receptor (PPAR) agonists, presents a promising approach for MASH treatment
RStudio Team, 2021)
Lancet (2021) 397(10284):157790
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