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This product is designed to support scientific investigations requiring a stable, precisely quantified source of GHK-CU in a nasal delivery medium

For anyone with these risk factors, personalised discussion with a clinician before and during semaglutide therapy enhances safety

Endocrinology (2013) 154:407888

Activation of GLP-1R also increases intracellular Ca 2+ through Ca 2+ release from the endoplasmic reticulum (ER) via the inositol 1,4,5 triphosphate receptors activated by PKA and the ryanodine receptors activated by Epac2 (9)

For medicines that must be maintained at 2C to 8C: Use a validated cool box or insulated travel case with a temperature monitor to maintain the cold chain Use ice packs or gel packs, but ensure they do not come into direct contact with the pen or vial, as localised freezing can damage the product Monitor the temperature throughout the journey where possible For medicines where the label permits storage at up to 25C or 30C for a defined period, an evaporative cooling wallet may be appropriate but only if the product label explicitly allows storage at those temperatures