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Gallbladder disease: Incretin-based therapies have been associated with an increased risk of cholelithiasis (gallstones) and cholecystitis (gallbladder inflammation), as noted in the UK SmPCs for licensed comparators such as semaglutide and tirzepatide
clinicians should follow current NICE guidance for obesity and type 2 diabetes in the interim
Making a pill version took special work so the medicine could survive in your stomach and be absorbed properly
In a dedicated MASLD trial, retatrutide resolved liver steatosis in more than 90% of participants at 48 weeks
[1] [4] It belongs to a class of medicines called glucagon-like peptide-1 (GLP-1) receptor agonists , which work by mimicking the action of a naturally occurring hormone that helps regulate blood sugar levels
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