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Semaglutide is a once-weekly injectable prescription medicine used in combination with a reduced-calorie diet and increased physical activity to help some people with obesity or overweight lose weight
It does not interfere with muscle protein synthesis in any direct pharmacological way
People who have gastrointestinal disorders like celiac disease or Crohn's disease or who have undergone weight-loss surgery may secrete too little hydrochloric acid or intrinsic factor
In fact, autoimmune chronic gastritis shows a very high degree of corpus and fundus atrophy of the stomach also featuring positive autoantibodies against parietal cells and/or intrinsic factor (49, 50)
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