Discussion Our findings elucidate an intricate relationship between abnormal serum lipids, particularly palmitoyl-L-carnitine, and neurodegenerative processes, highlighting a potential mechanism through which lipid dysregulation exacerbates conditions like AD
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Whether they ever will depends less on the receptor, whose biology is no longer in serious doubt, than on two engineering problems that the recent failures have brought into focus: getting the compound to the right neurons, and getting the right patients into the trial
A minority may have lingering mild symptoms beyond 4 weeks
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