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These supply problems are likely to cause uncertainty for many people living with type 2 diabetes. Davies added that the governments guidance should be commended for seeking clinical expertise from a range of multidisciplinary team members who work in the field of diabetes management to ensure clear guidance is available for clinicians dealing with these shortages
Some GLP strategies overlap with best practices
Interestingly, clinical trials reported to date on the effects of tirzepatide did include obese men and women, but results were not segregated by gender 47 , thus making it difficult to anticipate whether a sex dimorphism exist in GLP1/GIP responses
The natural history of NAFLD spans decades, so longer-term studies are needed to confirm whether GLP-1 agonists can prevent progression to advanced fibrosis, cirrhosis, or hepatocellular carcinoma
GLP-1 receptor agonist combinations with other weight loss agents have been explored in limited contexts
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