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Lee DS, Lee ES, Alam MM, Jang JH, Lee HS, Oh H et al (2016) Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate

Predicted contraindications: personal/family history of medullary thyroid carcinoma, MEN 2 syndrome, pregnancy, and history of severe pancreatitis

Early research suggests that Akkermansia muciniphila and Clostridium butyricum may influence pathways connected to GLP-1 signaling, but more research is needed

Many people do beautifully at lower doses

Titled Compound A and Compound B, the scientists are hoping that both can eventually be delivered in pill forms