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Many patients use the spray as a supplement with one -a-day spray along with once a week shot

In assays of neurotrophic activity, Dihexa has been found to be seven orders of magnitude more potent than brain-derived neurotrophic factor (BDNF), with demonstrated improvements in cognitive function in animal models of Alzheimers disease-like impairment

But the status quo, he argued, is no better

This includes people with: Pernicious anaemia (autoimmune destruction of intrinsic factor-producing cells), typically requiring lifelong IM injections Crohn's disease or surgical resection affecting the terminal ileum Coeliac disease causing malabsorption (may improve with gluten-free diet) Chronic pancreatitis reducing enzyme availability needed for B12 release Vegans and strict vegetarians need reliable B12 sources through fortified foods or supplements, as plant-based diets contain negligible amounts of active B12