Daily administration led to a 55% increase in IGF-1 levels at 2 weeks and 88% at 4 weeks
Diabetes Care 42 (6), 10751080
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N Engl J Med 345(12):851860 Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving H-H et al (2001Effects) Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy