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29 ClinicalTrials.gov (2020c)
55 The discovery of KIT and BRAF mutations and the development of novel immunotherapeutic agents that specifically target and inhibit these oncogenic pathways have provided new alternative treatments
In biologic manufacturing, PAT implementation has been slower than in small-molecule manufacturing, primarily because biologic analytical methods are more complex and often incompatible with inline or atline formats
These studies provide human pharmacokinetic and pharmacodynamic data, including confirmation of GH selectivity in human subjects
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