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More clinical evidence can be found on the role of GLP1R agonists such as exenatide can improve vascular endothelial dysfunction in diabetic patients, as has been found in this clinical trial by Hu et al., results suggested that exenatide improved the endothelial dysfunction reflected by digital reactive hyperemia index in newly diagnosed patients with T2DM, and the effect was not inferior to single metformin [59]
I feel sharper at work and more motivated throughout the day
These effects last as long as you keep taking a GLP-1 medication
Diabetes 54: 2734-2743, 2005
Supplementation with a combination of fish oil containing FAs and vitamins and minerals to males (W8-16) had no effect on POS-induced depressive-like behavior in the FST at W10-16 [122], while in females supplemented with choline, betaine, folic acid and vitamin B12 (P60-P186) the POS-induced depressive-like behavior was ameliorated in the FST at P165-186 [123]
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