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After the initial testing sessions, the 45 subjects were randomized to receive doses of 1.5 g, 3.0 g, or 4.5 g of glycine propionyl-l-carnitine (GPLC) for 4 weeks prior to a final testing session using the same protocol Results: Higher doses of GPLC actually had adverse effects on peak power (PP) and mean power (MP) compared to baseline values
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Olfactory dysfunction, including parosmia, has been associated with liraglutide use 46 , likely reflecting GLP-1R-mediated modulation of odor-evoked insulin secretion and foraging behaviors in the olfactory bulb 51,52
GLP-1 drugs may be prescribed for the following conditions as per American Diabetes Association/European Association for the Study of Diabetes (ADA/EASD) 2025 guidelines 11 : Primary glycaemic indication: GLP-1 RAs are recommended for adults with type 2 diabetes who have not reached their individualised A1C targets (typically when A1C is 1.5% above the agreed glycaemic goal) despite lifestyle measures and foundational therapy such as metformin
FDAs decision to halt production With the manufacturer Novo Nordisk now able to produce enough medication such that it is readily available, the FDA has ordered all pharmacies to stop making or selling compounded semaglutide
