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In clinical trials and post-marketing reports, a small percentage of patients have reported changes in skin sensations. This can manifest as tingling (paresthesia), numbness, or increased sensitivity
Skin Sensitivity Tests : A patch test can help gauge the risk of allergic reactions, especially for topical peptides
But this was before the rise of Mary Claire Haver and the social media menoverse
The dual-receptor approach may create a more balanced physiological response that reduces acute GI disruption
However, like any medication, it carries certain risks and side effects
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